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The HPV vaccine

The HPV vaccine has been in the news a lot lately, & it raises a number of interesting moral and ethical issues. Gardasil (made by Merck & Co) was approved in the United States and the European Union in 2006, & is also approved in a number of other countries. Cervarix, a similar vaccine by GlaxoSmithKline, is expected to be approved in 2007. They’re intended for females ages 9-26 (before their first sexual relationship).

The HPV vaccine has the honor of several “firsts” and “mosts”:

  • First vaccine for prevention of a cancer. (It would also reduce the number of abnormal Pap smears, procedures to evaluate abnormal Paps, & procedures on the cervix to remove abnormal tissue.)
  • First vaccine for prevention of a sexually transmitted disease.
  • First vaccine approved for only one gender (so far).
  • First vaccine (that I can think of) for prevention of an asymptomatic infection.
  • Most expensive vaccine so far (US$360 for the 3-shot series; plus the cost of administering the shots).
  • Most intense lobbying efforts (as far as I know) by a drug company in state legislatures, trying to get laws requiring vaccination passed.

Here are some of the issues:

  • Will (or could) HPV vaccination unintentionally promote sexual activity in teens and young adults?
  • Should a vaccine be required for school attendance if the condition it prevents is not acutely dangerous, and is not transmitted in the school setting?
  • Who should pay for HPV vaccination, especially if it’s mandated? Should tax dollars be used to vaccinate all females ages 9-26 who have medical coverage through government funded programs?
  • Is this a good use of resources?
  • How can developing countries, where cervical cancer is the 2nd most common cancer (far more cases than in the U.S.), afford/access/distribute HPV vaccine?

What do you think about the HPV vaccine? these issues? other issues?

Would you choose to have your child vaccinated if you were (or are) a parent?

Who should decide who gets HPV vaccine? Do you think HPV vaccination should be mandated?

Background on HPV and cervical cancer follows, for those who would like more information: Read the rest of this entry »

02-08-2007 |

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